Scientists believe that type 2 diabetes develops as a result of the body's inability to produce and use insulin correctly. Type 2 patients frequently have more insulin than is normally required, but because the body's cells are resistant to insulin, the insulin is not able to work as needed. As a result, type 2 patients may exhibit both high glucose levels and high insulin levels.
Researchers published the results of their study to treat type 2 diabetes with aspirin. They reported that high doses of salicylates, such as aspirin, reversed high blood sugar, high insulin and high blood fat levels in animal models by influencing a pathway in cells to use the body's own insulin more effectively.
Previously, aspirin had not been considered as a treatment for diabetes because of the potential serious side effects of aspirin therapy delivered in the high doses necessary to lower glucose levels. The risks of long-term aspirin therapy include dizziness, ringing sensation in the ears, and gastrointestinal problems.
However, as a result of this study, scientists believe that this cell pathway is a new target for drug development to treat type 2 diabetes.
If a drug could be developed with this capacity to lower blood sugars, but without high-dose aspirin's side effects, we could potentially have a potent new treatment for type 2 diabetes.
Source: Ivanhoe News
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